Emergency:

Helpline:

Radiation Oncology Therapy: How Radiation Therapy Is Used for Cancer Treatment

By Dr. Nagraj G. Huilgol in Nanavati Max Institute of Cancer Care , Head, Face and Neck Cancer Program

Apr 24 , 2023 | 4 min read

Radiation therapy, also known as radiotherapy, is a cornerstone oncology treatment that uses precisely controlled doses of ionizing radiation to kill cancer cells and shrink tumors. By radiotherapy definition, radiotherapy and oncology utilize a multidisciplinary approach to target malignant growths with extreme precision, damaging the DNA of cancer cells to prevent them from dividing and spreading. 

What is Radiotherapy and How Does Radiation Therapy Work?

To understand how radiation therapy works, one must look at the cellular level. When patients undergo radiation for cancer treatment, a specialized machine known as a Linear Accelerator (LINAC) or a radioactive source delivers high-energy beams to the tumor site. How does radiation work? It creates direct and indirect damage to the DNA within the cancer cells.

Unlike healthy cells, which have robust mechanisms to repair themselves, cancer cells are significantly more vulnerable. Once their DNA is damaged beyond repair, the cells stop dividing and eventually die. The body then naturally breaks down and removes these dead cells. It is important to note that radiation oncology treatment does not kill cancer cells immediately; it takes days or weeks of treatment before DNA is damaged enough for cells to die, and they continue to die for weeks or months after radiotherapy is completed. 

Also Read About Radiation Therapy for Breast Cancer

Types of Radiation Oncology Treatment

Oncology radiation is categorized based on the method of delivering radiation:

1. External Beam Radiation Therapy (EBRT)

External Beam Radiation Therapy (EBRT) uses specialized equipment to direct high-energy rays to the tumor from outside the body. Modern EBRT is highly sophisticated and includes:

  • IMRT (Intensity-Modulated Radiation Therapy): Adjusts the intensity of the beams to match the tumor’s shape.
  • IGRT (Image-Guided Radiation Therapy): Uses frequent imaging to ensure pinpoint accuracy during each session.
  • SBRT (Stereotactic Body Radiation Therapy): Delivers concentrated doses of radiation to small, well-defined tumors. 

2. Internal Radiation Therapy (Brachytherapy)

In this method, radioactive materials are placed inside the body near the cancer site. This technique allows for high-dose targeted treatment with minimal exposure to surrounding healthy tissues.

3. Systemic Radiation Therapy

This involves ingesting or receiving an injection of a radioactive substance (such as radioactive iodine) that travels through the blood to locate and kill cancer cells throughout the body.

The Radiation Oncology Process: What to Expect

Your journey through oncology radiation involves several key steps designed to ensure safety and efficacy:

  • Consultation: A Radiation Oncologist reviews your history and determines if radiotherapy is the right path.
  • Simulation (Treatment Planning): This is a "dry run" where you receive a CT Scan or MRI scan. The clinical team uses these images to map the exact coordinates of the tumor.
  • Dosimetry: Medical physicists calculate the exact dose of radiation needed to destroy the tumor while sparing the surrounding healthy organs.
  • Daily Treatments: Sessions usually occur five days a week for several weeks to allow healthy cells to recover during the weekend.

Importance of Radiotherapy for Cancer

Radiotherapy for cancer is also important in treating recurrent and remaining cancer cells. This treatment option is used to shrink tumors in early-stage cancer. Oncologists can combine radiation therapy and surgery to improve clinical outcomes. When used before surgery, it is called neoadjuvant therapy; when used after, it is called adjuvant therapy. It minimizes the chances of recurrence since radiation is exhaustive in killing cancer cells. Additionally, radiation therapy helps relieve symptoms (palliative care) of patients with advanced cancer by reducing pain caused by tumor pressure. 

Radiation Oncology Treatment for Children

Pediatric patients have to go for regular therapies 4 to 5 days a week for several weeks. Clinical protocols involve using small doses to ensure minimal damage to normal cells.

As such there are no restrictions on contact with family for children undergoing external radiation therapy. However, kids undergoing internal radiation therapy may be subjected to some restrictions. When internal therapy involves the placement of radioactive material inside the patient's body, the child may emit low levels of radiation for some time. Healthcare providers manage this by monitoring exposure levels to ensure family safety. Specialized centers can visit the child for brief intervals. Parents may be allowed to visit the child after some hours while following safety protocols, such as wearing protective gear if required.

Side Effects of Radiation Therapy

While highly effective, radiation therapy can have side effects, including:

  • Skin irritation (Radiation Dermatitis) and dryness.
  • Fatigue.
  • Localized hair loss (only in the area being treated).
  • Difficulty swallowing (if treating the head or neck).

These side effects typically subside post-treatment, but some cases may require supportive care. We recommend you discuss the whole procedure with a radiation oncology specialist in detail.


Frequently Asked Questions

1. What is The Success Rate of Radiation Therapy for Cancer Treatment?

Radiation therapy has a high success rate, particularly for early-stage cancers when combined with other treatments.

2. Are There Alternatives to Radiation Therapy?

Yes, alternatives like chemotherapy, immunotherapy, and surgery may be considered based on the cancer type and stage.

3. Can Radiation Therapy Be Used Alongside Surgery?

Yes, it is often used before or after surgery to enhance treatment effectiveness and prevent recurrence.

4. Is Radiation Therapy Safe for Children?

Radiation therapy for children is carefully planned to minimize side effects and maximize safety.

5. How Long Does a Radiation Therapy Session Take?

Each session typically lasts 15-30 minutes, but the overall treatment duration may extend over weeks.

 

Medical Disclaimer: The information provided in this article is for educational purposes only and does not constitute medical advice. Treatment decisions should be made in consultation with a qualified oncologist. Decisions regarding specialized cancer care may involve significant emotional and financial considerations. 

References

1. American Society for Radiation Oncology. (2023). Safety and Quality in Radiation Oncology.
https://www.astro.org/Patient-Care-and-Treatment/Radiation-Therapy-Information

2. National Cancer Institute. (2022, January 10). Radiation Therapy to Treat Cancer.
https://www.cancer.gov/about-cancer/treatment/types/radiation-therapy


3. International Atomic Energy Agency (IAEA). (2021). Introduction to Radiotherapy.
https://www.iaea.org/resources/radiotherapy


4. World Health Organization. (2021). Radiation therapy equipment inventory and oncology services.
https://www.who.int/cancer/publications/radiation_therapy/en/